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CANC-013B
[Lys(Me2)382]-p53 (377-387); p53K382Me2
Thr-Ser-Arg-His-Lys-Lys(Me2)-Leu-Met-Phe-Lys-Thr
Size:1mg
P1(RMB):1277
MW:1404.7
One letter sequence:TSRHK-K(Me2)-LMFKT
Molecular Formula:
Description:p53K382Me2 is derived from amino acid residues 377-387 of human p53 tumor suppressor protein, with dimethylation at Lys382. DNA damage induces increased levels of this peptide, which is recognized by p53-binding protein 1 (53BP1). 53BP1 interacts with p53 and modulates its transactivation.
Literature Reference:Kachirskaia, I. et al. J Biol Chem 283, 34660 (2008).
Cas: